Abstract: The performance of minimum output energy(MOE) detector will significantly degrade when the weight vector is affected by the noise.In order to resolve this problem,a noise suppression based linear conjugate MOE detector is designed. The constrained least mean square(LMS) algorithm is applied to the new MOE detector and a blind noise suppression based linear conjugate MOE multi-user detection algorithm based on constrained LMS is proposed.The proposed algorithm eliminates the noise in the weight vector and utilizes the complex conjugate of the received vector.Thus the output signal-tointerference -plus-noise-ratio(SINR) and bit error rate(BER) performance is improved.Simulation results demonstrate that the proposed algorithm is of better performance.