分式布朗运动（FBM）分维模型对生物大分子构象机理的描述

USING FRACTIONAL BROWNIAN MODEL (FBM) TO DESCRIBE THE CONSTRUCTION ORGANISM OF THE BIOLOGICAL MACROMOLECULE

摘要: 利用FBM分形模型以白内障为样本，进行了构象机理的研究．首先认为生物大分子-蛋白质凝聚运动的最好描述是FBM；其次，对由于蛋白质构象运动而产生的白内障的宏观性质进行了图象纹理分析；把白内障图象按不同的窗口大小和展开方式由二维数据展成一维数据，用极大似然估计MLE方法估算H值，进行白内障图象的区域分割和特征抽取．最后给出最佳窗口大小和展开方式为6×6和圆形方式，Hurst指数是描述白内障的定量参数．

Abstract: The paper uses the FBM model to study the construction or ganism,catar act as the sample.First of all,hold that the best description of biological macromo lecule-protein is FBM model. Secondly,apply the image texture analysis to the cat aract macro properties; extend the two dimensional catar act data into one dimensional data according to the different window size and spreading style; use the maximum likelihood estimation (MLE) method to estimate the Hvalue; then accomplish the segmentation and feature selection. Finally,pointout that the best window size and spreading style is 6?6 and circler espectively,and that the Hurst parameter is the quantitative parameter of cataract diag nosis.