Abstract: In CIMS system of industrial enterprises, the communication of management computer and the plant floor equipments is an important sector. Base on the hardware communication of computer control system in some enterprises, the paper studies the design and application in a real computer communication system ff CIMS with plant floor equipments. It focuses on the design and application of network structure of MIS with plant floor equipments in their level of automatic control and computer processing. The real application shows that the design on this system is a reliable, economical and workable method for communication Of CIMS and It's plant floor equipments.