Abstract: This paper for the first time in China makes an effort on port simulation using GPSS-F.In this paper weconstruct a complete port simulation model including vessel,vehicle,lighter and port itself,and put forward aset of parameter method and a criterion of overall efficiency of port.Using this model we can study a series ofproblems of port programming and management.And based on a port division of Shanghai,we have made apractical study about the optimal number of berthes and the optimal proportion of goods without throughdepot as an application of this model.